Substance use, misuse and dependence: A PLOS Medicine special issue

This week sees publication of the first research papers that will form part of

Opioid-related gifts from pharma companies linked to physician prescribing by specialty

Physicians who received gifts from pharmaceutical companies related to opioid medications were more likely

Thirty-three percent of people on anticoagulants take OTC supplements with potentially serious interactions

Nearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban used over-the-counter

Half of all commonly used drugs profoundly affecting the gut microbiome, warn experts

A new study presented at UEG Week 2019 reports that 18 commonly used drug

Resistance to antibiotics doubles in 20 years, new study finds

Resistance to commonly-used antibiotics for treating harmful bacteria related to a variety of stomach

Estuarine waters hold promise in global pain-relief hunt

The worldwide search for an opioid alternative has made a leap forward—with a scientific

A Canadian essential medicines list must be evidence-based

An essential medicines list in Canada should be evidence-based and independent of conflicting interests,

Antidepressant medications appear to be generally safe

Antidepressants are generally safe, according to a new study by an international team of

Rituxan approved for pediatric patients with rare vasculitis diseases

(HealthDay)—Rituxan (rituximab) injection was granted the first approval for a drug to treat granulomatosis

Targeted therapy slows progression of advanced prostate cancer

Targeting faulty DNA repair mechanisms in advanced castration resistant prostate cancer can slow progression

Treating C. difficile infections: New purpose for an old drug?

Common in hospitals and nursing homes, Clostridioides difficile infection (CDI) is a major health threat,

Nearly one in three patients with lupus use prescription opioids for pain

Although there is little evidence that opioids effectively reduce pain from rheumatic diseases, a

Marijuana use common among adults with medical conditions

(HealthDay)—Marijuana use is common among adults with medical conditions, especially younger people, according to

Low-cost blood pressure drug improves brain function in individuals with autism

Drugs known as “beta-blockers” have been used since the 1960s as a low-cost, safe

Purdue Pharma begins Chapter 11 bankruptcy journey

Purdue Pharma gets its day in court Tuesday after the OxyContin maker filed for

Two lung cancer drugs approved and one rejected for NHS Scotland

An immunotherapy and a targeted treatment have been recommended for use on the NHS

Failed cancer drug looks promising for scleroderma and other fibrotic conditions

Sixteen years ago, a research group at Mayo Medical School published results showing that

Chaotic talks show challenge of reaching opioid settlement

For months, the judge overseeing national litigation over the opioids crisis urged all sides

Compound offers prospects for preventing acute kidney failure

Russian researchers from the Moscow Institute of Physics and Technology, the Institute of Cell

Drug designed to treat metastatic pancreatic cancer may help extend life

A drug developed by researchers at the Renaissance School of Medicine at Stony Brook

Post opioid-overdose interventions emerge in US

Opioid-related deaths continue to take the lives of thousands in the U.S. each year,

Study shows hazardous patterns of prescription opioid misuse in the US

Among adults aged 18 years and older, 31 percent used prescription opioids only as

Research explores the use of new psychoactive substances by young people

A research study into New Psychoactive Substances (NPS)—formerly referred to as ‘legal highs’—provides new

New drug shows encouraging survival in pancreatic cancer

A clinical trial testing a new drug in pancreatic cancer had promising initial results,

Prescription drug misuse common in high schoolers

(HealthDay)—Misuse of prescription drugs is common among high school students, and those misusing prescription

Chemists teach old drug new tricks to target deadly staph bacteria

“Slaying superbugs, one antibiotic at a time,” is the motto of Bill Wuest’s chemistry

Drug trial shows efficacy in treating anemia in chronic kidney disease patients without dialysis

FibroGen, Inc. today announced publication of results from the Phase 3 trial of the

Nonprescription antibiotic use seems prevalent in the United States

Nonprescription antibiotic use appears to be prevalent in the United States, according to a

Eye drops, ointments sold at Walgreens recalled

(HealthDay)—A number of over-the-counter eye products sold at Walgreens have been recalled by manufacturer

Adding bevacizumab improves overall survival in NSCLC

(HealthDay)—The addition of bevacizumab to carboplatin/pemetrexed is associated with improved overall survival among patients