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Mice can be used to study the neural circuits underlying complex decision-making, suggests an analysis of more than 500,000 mouse decisions reported in JNeurosci. Some of the most advanced tools in neuroscience are developed for use with mice, yet studies of behaviors most relevant to humans typically involve other model organisms. Anne Churchland and colleagues addressed this gap by investigating […]
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UK researchers behind a potential ‘universal’ liquid biopsy blood test for cancer detection have licensed the technology to an industrial partner to take it to market. The research team believes that the test could be the first screening tool to ‘rule in, or rule out’ cancer in patients under suspicion of the disease, alongside other traditional diagnostics methods. The test […]
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In traditional mammography screening, all breast tissue is captured in a single image. Breast tomosynthesis, on the other hand, is three-dimensional and works according to the same principle as what is known as tomography. This means that several low-dose X-ray images are taken of the breast from different angles, which are reconstructed by a computer to show thin layers of […]
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Only a small proportion of cases of dementia are thought to be inherited—the cause of the vast majority is unknown. Now, in a study published today in the journal Nature Communications, a team of scientists led by researchers at the University of Cambridge believe they may have found an explanation: spontaneous errors in our DNA that arise as cells divide […]
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October 11, 2018 — Trevena, Inc. (NASDAQ: TRVN), today announced the outcome of the meeting of the U.S. Food and Drug Administration (FDA) Anesthetic and Analgesic Drug Products Advisory Committee (AADPAC) to review and discuss oliceridine. At the meeting, the Advisory Committee voted 8 against, and 7 in favor of, the approval of oliceridine for the management of moderate to […]
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In follow-up to the I HART CGM study, which showed the benefit of real-time continuous glucose monitoring (RT-CGM) compared to flash monitoring for time spent in hypoglycemia among adults with type 1 diabetes at high hypoglycemia risk, researchers conducted an extension trial that assessed the effects of continuing RT-CGM or switching from flash to RT-CGM of the subsequent 8 weeks. […]
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Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine in St. Louis. In the United States, overall rates of new colorectal cancer cases and deaths from […]
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People with type 1 diabetes are far more likely to develop cardiovascular disease than those without diabetes. Their risks climb even higher if they show signs of hypertension (high blood pressure) or dyslipidemia (unhealthy levels of cholesterol or triglycerides). Interviewing both teens and parents, Joslin Diabetes Center researchers have identified strategies to help teens with these conditions manage them better, […]
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Despite an efficient and well-tolerated vaccine, hepatitis B (HBV) remains a major public health problem, with more than 250 million people at high risk of developing liver cirrhosis and cancer as a result. HBV treatment must be given for life, as it does not produce long-term disease control. A new animal study published in The FASEB Journal reveals a significant […]
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An antimicrobial signaling molecule called IFNλ4 has lower activity against the hepatitis C virus in the vast majority of humans compared with chimpanzees and African hunter-gatherer Pygmies, according to a study published October 11 in the open-access journal PLOS Pathogens by John McLauchlan’s research team at the MRC-University of Glasgow Centre for Virus Research in the UK, and colleagues. As […]
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